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Writer's pictureMarcelo Serafim

Understanding Cancer


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Cancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells. These cells can invade and damage surrounding tissues, and they often have the ability to travel through the bloodstream or lymphatic system to form new tumors in distant parts of the body. While cancer can be a frightening diagnosis, advancements in treatment and research bring hope to patients and their families.



Cancer develops when there are changes, or mutations, in the genes that control how our cells function. These mutations can be inherited from our parents or acquired throughout our lives due to factors like exposure to carcinogens, lifestyle choices, or simply aging. Regardless of the cause, these genetic changes lead to cells that multiply out of control, eventually forming a mass of tissue called a tumor.


There are over 100 different types of cancer, and they're usually named after the organs or tissues where they originate. The most common types of cancer worldwide include:


  • Lung cancer: The leading cause of cancer death.

  • Breast cancer:  The most common cancer in women.

  • Prostate cancer: The most common cancer in men.

  • Colorectal cancer: Cancer of the colon or rectum.

  • Skin cancer: Comes in various forms, with melanoma being the most dangerous.

Fortunately, cancer treatment has experienced significant progress in recent decades. Traditional therapies like surgery, radiation therapy, and chemotherapy remain vital tools in fighting cancer. However, newer approaches are offering more targeted and personalized treatments, often with fewer side effects.



Some examples of these advancements include:

  • Immunotherapy:  Stimulates the body's own immune system to fight cancer cells.

  • Targeted therapy:  Uses drugs designed to interfere with specific molecules involved in cancer growth and survival.

  • Precision medicine:  Customizes treatment based on the genetic makeup of a patient's tumor.


 

Cancer thrives on uncontrolled cell growth. Chemotherapy, a cornerstone of cancer treatment, works by essentially fighting fire with fire. These powerful drugs target rapidly dividing cells, aiming to disrupt their growth and eliminate cancerous ones.


Targeting the Cell Cycle

Imagine a cell's life as a series of stages, called the cell cycle. Chemotherapy drugs disrupt specific stages in this cycle, preventing cancer cells from replicating their DNA or dividing into new cells.

  • DNA Disruption: Some drugs damage the DNA within cancer cells, making it impossible for them to copy the instructions needed for division.

  • Division Blockade: Other drugs target the cell division machinery itself, preventing the cell from splitting into two new daughter cells.


A Systemic Approach

Unlike surgery or radiation therapy, which target specific areas, chemotherapy drugs travel throughout the bloodstream. This makes them effective against cancer cells that may have spread beyond the initial tumor site.


Not Without Consequences

While chemotherapy primarily targets fast-growing cells, healthy cells like those in the hair follicles, bone marrow, and digestive tract can also be affected. This is why some common side effects like hair loss, fatigue, and nausea occur.


A Tailored Approach

Chemotherapy is rarely a one-size-fits-all treatment. Oncologists personalize treatment plans based on the specific type and stage of cancer. This may involve using a single drug or a combination, with careful consideration of dosage and timing. Often, chemotherapy is combined with other therapies like surgery or radiation for a more comprehensive attack on cancer.


Hope on the Horizon

Chemotherapy remains a powerful tool in the fight against cancer. Continued research is leading to the development of new, more targeted drugs with fewer side effects. This ongoing pursuit offers a brighter future for cancer patients.

 

Questions

  1. What are some factors that can increase my risk of cancer?

  2. How can I reduce my risk of developing cancer?

  3. What are the early warning signs of cancer?

  4. What screening tests are recommended for my age and gender?

  5. If someone I love is diagnosed with cancer, how can I support them?


 

Vocabulary

  • Carcinogens: Substances that can cause cancer.

  • Lymphatic system: A network vessels and organs that helps the body fight infection.

  • Malignant:  Describes cancerous tumors that have the ability to spread.

  • Metastasis: The process of cancer spreading from its original site to other parts of the body.

  • Oncologist: A doctor who specializes in treating cancer.


Phrasal Verb

  • Fight off (to defeat or resist)

  • Example: The patient's immune system was able to fight off the early stages of cancer.

American Idiom

  • Kick the bucket (to die)

  • Example: Sadly, after a long fight with cancer, my grandfather kicked the bucket last year.


 

Grammar Tip

Adjectives and adverbs are often used in writing about cancer. Adjectives describe nouns (e.g., cancerous cells, aggressive tumor), while adverbs modify verbs, adjectives, or other adverbs (e.g., the tumor grew rapidly, a highly effective treatment).


 

Listening



 

Homework Proposal

Research one of the newer forms of cancer treatment discussed in the article (immunotherapy, targeted therapy, or precision medicine). Write a short summary explaining how the treatment works and its potential benefits for cancer patients.

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